INTRODUCTION

Preface

In 1848 Marx and Engles wrote "Modern industry has established the world market ... All old established industries have been destroyed or are daily being destroyed ... In place of the old local and national seclusion and self-sufficiency, we have universal inter- dependence of nations. As in material, so also in intellectual production. The intellectual creations of individual nations become common property." (Kobrin, 1991). This was true in the middle of the 19th century and it is even truer today. At the dawn of a new millennium we enter the four dimensional invisible continent described by Kenichi Ohmae. The dimensions of this world are old economy commerce; a borderless world in which capital moves around, chasing the best products and the highest investment returns regardless of national origin; the cyber-world; and the high multiples awarded to new economy stocks which underpin the pensions of many people (Ohmae, 2000). In this chaotic New World, it is especially important that the knowledge transfer be as fast and accurate as possible.

In this chapter, the background to the research issue, technology transfer to multinational medical device and pharmaceutical companies manufacturing in Ireland is introduced. The reason that this area was chosen as a subject for study is elucidated. The specific research questions are outlined. The expected benefits of the research are presented. And finally an outline of the thesis is presented.

Background to the Research

The author is employed in Ireland by a multinational medical device manufacturer. He is a knowledge worker with higher degrees in technology. At the beginning of his period of employment he was sent as part of a team for over 6 months to the firm's American headquarters. The team members' objective was to assist with the completion of the development of a new manufacturing process and learn as much about it as necessary to transfer the technology back to Ireland.

The first objective was achieved very successfully and the talented Irish knowledge workers made a major contribution to the completion of the development work and its introduction into operation in the USA. However, when the technology was transferred to Ireland a short time later, a number of difficulties were encountered with the transfer process. And while all these difficulties were overcome, the question was asked about why they occurred and how the process could have been managed better.

Technology Transfer

A detailed account of research on technology transfer is presented in Chapter 2. In general, Technology Transfer is the transfer of a process, product manufacturing knowledge, or other technical equipment or know-how from one organisation or individual to another. The term has different meaning depending on the context. Within one nation Technology Transfer often refers to the transfer of a new idea or invention from a University or Government research institution to a private firm for commercialisation. Technology Transfer may refer an inter-firm licence transfer of intellectual property such as know-how, patents, trademarks, copyrights, blueprints, trade secrets, methods, formulas, customer lists, manuals, etc.

This study is concerned with International Technology Transfer, which refers to the transfer of technology across national boundaries. There are five generic categories (Simon, 1991): (1) international technology market; (2) intra-firm transfer; (3) government-directed agreement or exchanges; (4) education, training, conferences; (5) pirating or reverse engineering. The first two are generally of most interest to business, although business is also concerned to limit its losses as a result of the last. Three classes of Technology Transfer can be distinguished. Material-transfer is the transfer of finished goods, which some do not consider to be technology transfer since "know-how" is not transferred. Design-transfer involves the transfer of designs, blueprints, and the know-how to manufacture previously designed products and equipment. Capacity-transfer is the transfer, not just of the capability to manufacture existing products, but of the capability to adapt existing products and develop new ones. How technology is transferred depends on the resources needed. The possible modes of International Technology Transfer considered by Tsang (1997) in order of increasing resource need were (a) exporting, (b) licensing, (c) joint ventures, and (d) wholly owned subsidiaries. This study is primarily concerned with transfer to wholly owned subsidiaries. There are a number of reasons why companies pursue a globalisation strategy.

International firms can exploit differences in prices and resource availability between countries. This may mean producing labour intensive goods in countries with cheap labour rates or where raw materials are abundant and cheap, or producing technologically advanced products or conducting advanced research in countries with high levels of education (Kogut, 1985). Firms may want to be multinational to benefit from the transfer of knowledge between subsidiaries in different countries, to increase the return on R&D by being in as many markets as possible, to exploit ambiguous national jurisdictions, to subsidise across markets, to diversify markets so as not to be too dependent on the fortunes of one market, and to scan for new technologies and market opportunities world wide. Firms gain operational advantages from being in all major world-wide markets. There can be significant transnational economies of scale.

The major reasons for locating manufacturing sites have been changing. For many manufactured goods the labour component of manufacturing costs has been decreasing (Aharoni, 1991). Reductions in transport costs have lessened the importance of proximity to markets. The effect of international trade agreements and organisations has lowered regulatory barriers to the free movement of goods and services.

Ireland is benefiting from these trends. The rising labour rates are not of major concern to high-technology industries such as computers, electronics and pharmaceutical industries, although more labour intensive industries such as textiles are closing and moving to lower cost locations. The shortage of highly skilled labour is a greater problem. The reduction in transport costs, and indeed to high value to weight ratio of high technology products, lessens the disadvantage of Ireland's location as the outer island of an archipelago on the periphery of Europe. Ireland's membership of the European Union and Euro-zone complement the advantages accruing from its well-educated workforce and favourable corporate taxation rates.

Multinational Healthcare Industry Companies in Ireland

Many overseas multinational manufacturing companies have been attracted to Ireland. The firms have been lured with financial incentives such as grants for employing people, by a favourable tax regime (10% taxation on corporate profits), the availability of an educated relatively cheap workforce, and a manufacturing location within the EU. Since the 1970's a number of large multinational pharmaceutical companies established manufacturing operations in Ireland. Originally, these firms were also attracted by availability of suitable green-field sites for locating chemical plants and (at the time) more relaxed environmental laws. Many of these firms continue to expand (e.g. Merck in Clonmel, Pfizer and Novartis in Ringaskiddy). Typically bulk pharmaceuticals and pharmaceutical intermediates have been produced from imported raw materials and intermediates. Bulk pharmaceuticals are often exported for further processing and tableting. Many of the companies adjust their transfer prices to benefit from Ireland's favourable corporate tax regime. The pharmaceutical industry has been a success for the IDA. The cost of construction, permanent nature of chemical plant installation, and cost and regulatory difficulties with building plants elsewhere, have enticed nearly all bulk pharmaceutical operations attracted to remain in operation. With so many companies continuing to expand, the industry should remain large for many years to come. Many other Healthcare companies including medial device manufacturers have located in Ireland in recent years. Many of these companies produce medical devices or tablets. With the ageing of the post-war baby boom generation in America and Europe and advances in technology, these industries are expanding considerably at present. Ireland is popular with American companies locating European manufacturing sites. The advantages of Ireland are the availability of an educated English-speaking workforce, entry into the Euro zone (compared with UK), an extra hour of business overlap time (compared to continental Europe), and low corporate tax rates.

Technology Transfer within Healthcare Industries

Regulation of the pharmaceutical and medical device industries by organisations such as the Food and Drug Administration in the USA is strict. The medical profession is concerned about patient welfare and malpractice suits, and therefore conservative about choices of drugs and medical devices. Both factors restrict entry to the marketplace and lengthen product cycles by comparison with the electronics industry. The length of time from initial development to market is long, allowing enough time for transfer of technology from R&D to manufacturing. But patent expiry and advances in technology do limit product life and compress the traditional 6-stage international product life cycle somewhat (Aggarwal, 1991, p. 64).

The Research Issue and Objectives

This research will focus on the issue of technology transfer to Irish subsidiaries of medical device and pharmaceutical companies from their international parent. Every time another multinational sets up in Ireland it must transfer technology for start-up. As products and manufacturing processes change more technology must be transferred to implement the changes. Technology flow back is also possible if the Irish subsidiaries improve the original methods.

Research Approach

The primary focus of research can either be quantitative or qualitative depending mainly on how well defined the objectives of the study are. A quantitative study would be used for causal and predictive studies when the dimensions of the problem are well defined. A qualitative study would be used for exploratory studies when the dimensions are less well defined.

There has already been much study of technology transfer between affiliates of multinational companies. For this reason the methods of conducting technology transfer and the various approaches taken are well known. The literature review was sufficient to reveal useful questions to ask. Also it was preferred that questions related to the benefit of various strategies could be answered with certainty. For these reasons, a primarily quantitative approach was preferred.

Typical quantitative studies require larger samples than qualitative studies. Questions are usually pre-set. In quantitative studies questions may be open-ended. In quantitative studies the researcher is usually not involved. Therefore, a mail survey was chosen for the research. It is well suited for gathering a lot of data using pre-set questions. The author chose not to include his own company's experiences in the final study to maintain uninvolvement.

Research Questions

The objective of this research is to ascertain how successfully multinational pharmaceutical and medical device companies have managed the process of technology transfer into Ireland. After reviewing the literature the key issues were determined. The effects of nationality of parent, size of the subsidiaries, the duration of their establishment in Ireland and their degree of autonomy, on the smoothness of technology transfer, as measured by adherence to the schedule and budget is assessed. The benefits or otherwise of techniques, such as travel by Irish based employees to the head office or other company sites and travel by other employees to Ireland is assessed. The effect of quality of training and documentation is measured. The effect of the 'newness' of the technology and the application of various business improvement initiatives on the success of technology transfer is assessed. The knowledge gained by those involved in the transfer process that could help them transfer technology more efficiently in future is also gauged. The extent of Research and Development by the Irish subsidiaries is measured and compared with technology transfer capabilities.

Methodology

After reviewing previous published work on the issue of technology transfer, the key issues that may affect the technology transfer process were identified. It was decided that the main method of collection of primary sources of data to be used was a postal survey of managers involved in managing technology transfer to multinational pharmaceutical and healthcare companies operating in Ireland.

A case study of a transfer process with which the author was familiar was considered as the methodology. It would have answered a number of questions about why this particular process was not perfect. However, the sources of knowledge would be limited to those within the company and as such would fail to benefit from the broader experiences of other.

A questionnaire was written to ask questions highlighted in the review of the literature and was fine-tuned by testing on personal acquaintances of the author. The questionnaire was kept as brief as possible and multiple-choice answers were preferred for most questions. Two open-ended questions were included to seek new ideas. These questions were a small part of the survey and are used for supplementary analysis. Once revised the questionnaire was sent to managers of Irish subsidiaries of multinational pharmaceutical and medical device manufacturers firms who transferred technology into Ireland. The returned questionnaires were analysed.

Analysis was conducted using Excel. The first part of the analysis was to edit the responses and get a feel for the data (Sekaran, 1992). After examination of the data it was decided that a composite variable called TTE (Technology Transfer Effectiveness) be the major 'effect' against which the various causal and predictive variables be examined. TTE is a combination of variables relating to adherence to technology transfer schedule and budget.

Additional results were obtained from the open-ended questions. These are based on the recommendations of the participants concerning their technology transfer experience.

Discussion and Strategy Recommendation

The results from the analysis are discussed and compared with previous research unearthed in the literature survey. Technology transfer to healthcare and pharmaceutical companies in Ireland is compared with similar studies of other industries in other countries. The actions that are most and least beneficial are highlighted. Finally, recommendations on the effectiveness of some processes and methods on technology transfer processes of multinational pharmaceutical and healthcare companies operating in Ireland are formulated.

Significance of the Study

The study is significant because the area has not been examined in detail in any published work. There have been some studies of more general aspects of technology transfer and of technology transfer in other industries in other countries. Multinational industries are one the most important parts of the Irish economy providing well-paid employment and significant balance of payment advantages. The strategic actions by the government have encouraged this influx and Ireland is now the world leader for exporting software. The healthcare and pharmaceutical industries are increasingly important as the American and European post-war baby boom generation ages. The number of firms setting up or expanding operations continues to grow. With each of these growth phases, technology transfer is required. This study attempts to improve the knowledge of this increasingly important subject matter.

This study presents results relating the effects of company characteristics and technology transfer practices to technology transfer effectiveness. It present an important new measure TTE (Technology Transfer Effectiveness), a composite of adherence to schedules and budgets, as a measure of technology transfer performance to compare the effect of characteristics and practices. Results of the relationship of R&D in Ireland to technology transfer effectiveness are presented. It was found that the number of companies conducting R&D in Ireland has increased significantly in recent years. The results of this study will be promulgated to those respondents who requested it. This will allow the learning in the work to be applied to the benefit of those transferring technology into Ireland.

Structure of the Thesis

There are a total of seven chapters and three appendices in this thesis. In Chapter 2 literature pertaining to the background areas of globalisation strategy and knowledge diffusion are presented. More specific studies of International Technology Transfer are then outlined. In Chapter 3 the methodology of the research is described which include reasons for the choice of methodology and the details about its execution. In Chapter 4 the research finding are presented. The results of the detailed quantitative analysis and brief qualitative studies are included. In Chapter 5 the findings are discussed with respect to 24 hypotheses derived from the literatures. In Chapter 6 conclusions and recommendations are derived. In Chapter 7 the bibliography of the study is presented. In the Appendix the verbatim comments are presented.